litaba

Tlhahlobo ea morao-rao e phatlalalitsoeng ke sehlopha sa lipatlisiso tsa mahlale sa Canada e fana ka maikutlo a hore li-cannabinoids li ka bapala karolo ho thibela le ho alafa COVID-19 le COVID-19 ea nako e telele.

Tlhahlobong e felletseng, sehlopha sa bo-ramahlale ba Canada se fana ka leseli le khahlisang mabapi le karolo e ka bang teng ea li-cannabinoids ho loants'a vaerase ea COVID-19.Boithuto bona, bo bitsitsoeng "Cannabinoids le Sistimi ea Endocannabinoid ho Bakuli ba Pele ba SARS-CoV-2 le bakuli ba sa foleng ba COVID-19," e ngotsoe ke Cassidy Scott, Stefan Hall, Juan Zhou, Christian Lehmann le ba bang mme e phatlalalitsoe ho Journal of SARS-CoV. -2″ makasine.

Meriana ea Meriana.Ka ho sekaseka lintlha tse ngata tse tsoang lithutong tse fetileng, tlaleho e bua ka hore na likarolo tsa semela sa cannabis li ka bapala karolo ea bohlokoa joang ho thibela ho qala ha COVID-19 le ho fokotsa litlamorao tsa eona tsa nako e telele.Liphuputso li fana ka maikutlo a hore li-cannabinoids, haholo-holo tse nkiloeng semeleng sa cannabis, li ka thibela ho kena ha kokoana-hloko ka liseleng, tsa fokotsa khatello ea oxidative e kotsi, le ho hatella karabelo ea 'mele ea ho itšireletsa mafung hangata e bonoang maemong a matla.Boithuto bona bo boetse bo totobatsa karolo e ka bang teng ea cannabinoids ho sebetsana le matšoao a fapaneng a tsoelang pele a COVID-19 ea nako e telele.

Ho latela thuto, li-cannabinoids li na le monyetla oa ho thibela ho kena ha vaerase, ho fokotsa khatello ea oxidative le ho fokotsa sefefo sa cytokine se amanang le vaerase ea COVID-19.Liphuputso li bontša seo ka ho tobalihlahisoa tsa cannabinoide ka theola maemo a enzyme 2 e fetolang angiotensin (ACE2) liseleng tsa bohlokoa, kahoo e thibela likokoana-hloko ho kena liseleng tsa motho.Bafuputsi ba hlokometse hore sena se bohlokoa haholo ha ho fanoa ka karolo ea ACE2 e le monyako oa mantlha oa ho kena ha vaerase.Tlaleho e boetse e bua ka karolo ea cannabinoids ho sebetsana le khatello ea oxidative, ntlha ea bohlokoa ho pathogenesis ea COVID-19.

Ka ho fetolela li-radicals tsa mahala hore e be mefuta e sa sebetseng hantle, cannabinoids joalo kaCBDe ka thusa ho fokotsa litlamorao tse mpe tsa khatello ea oxidative maemong a matla a COVID-19.Ho latela thuto, cannabinoids le tsona li ka ba le litlamorao ho lifefo tsa cytokine, karabelo e matla ea 'mele ea ho itšireletsa mafung e bakiloeng ke COVID-19.Li-cannabinoids li bonts'itsoe li sebetsa hantle ho fokotsa li-cytokine tse ruruhileng, tse fanang ka maikutlo a bokhoni ba tsona ba ho laola likarabo tse joalo tsa 'mele.

Nako e telele ea COVID e bua ka boemo boo hangata bo hlahang joalo ka phetoho ea COVID-19 ho isa boemong bo sa foleng.Lipatlisiso li senola bokhoni ba cannabinoids ho phekola matšoao a tsoelang pele a ho tepella maikutlong, ho tšoenyeha, khatello ea kelello ka mor'a ho sithabela maikutlo, ho hlobaela, bohloko le ho lahleheloa ke takatso ea lijo.Sistimi ea endocannabinoid e phetha karolo ea bohlokoa tšebelisanong ea lits'ebetso tse fapaneng tsa methapo, e etsa hore e be sepheo sa kalafo ea matšoao ana a neuropsychiatric.

Boithuto bo boetse bo lekotse mekhoa e fapaneng ea tšebeliso le mefuta e fapaneng ea lihlahisoa tsa cannabis tse sebelisoang ke bareki.Lipatlisiso li bontša hore ho hema ka ho hema ho ka 'na ha e-ba le liphello tse mpe ho batho ba nang le maemo a ho hema, ho thibela liphello tsa eona tsa phekolo."Le ha ho tsuba le ho tsuba hangata e le mekhoa e ratoang haholo ho bakuli ba cannabis hobane ba qala ho nka khato ka potlako, melemo e ka bang teng ea kalafo ea cannabinoid e ka fokotsoa ke litlamorao tse mpe tsa ho hema bophelo bo botle ba phefumoloho," ho boletse bafuputsi.Boithuto bo bonts'a "Bakuli ba sebelisang cannabis vaporization ba na le matšoao a fokolang a phefumoloho ho feta ho tsuba hobane sesebelisoa sa vaporizer ha se chese cannabis hoo e ka tukang."Bangoli ba tlaleho ba hatisa tlhokahalo ea lipatlisiso tse eketsehileng sebakeng sena.Leha liphetho tsa pele li khothatsa, li hlokomelisa hore ke tsa selelekela 'me li tsoa lithutong tse sa tobang ka COVID-19.Ka hona, lithuto tse shebiloeng haholoanyane le tse felletseng, ho kenyeletsoa liteko tsa bongaka, li bohlokoa ho utloisisa ka botlalo karolo le katleho ea li-cannabinoids ho alafong ts'oaetso ea SARS-CoV-2 ea pele le e hlobaetsang.Ho feta moo, bangoli ba buella lipatlisiso tse tebileng tsa pharmacology le mekhoa ea phekolo e ka 'nang ea e-ba teng ea tsamaiso ea endocannabinoid mme ba khothalletsa sechaba sa saense ho hlahloba mokhoa ona ka matla.